They said I can get retested and said maybe cause blood had to fly from nz to au? The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. Their reasoning is that it affects their accuracy numbersand they don't want to skid away from the 99%. Thanks for sticking with us for a full year. I actually have an auto immune disease so they think thats why. I met with a genetic counsellor who reviewed my file, age and risk, nd we decided together no further testing was needdd however for peace of mind and funsies we did the quad test which is a hormone test and can flag for trisonmies. How far along are you currently? Thank you for sharing, as the Natera Panorama has really freaked me out. 5/23: 3rd beta: 4000.6 + saw gestational sac and yolk sac. When a medical test is performed in a patient for a particular purpose, it is possible that the test will identify an unexpected abnormality that is not related to the initial reason for doing the test. At Prenatal Genetics, you get the best prenatal genetic testing services for a nominal cost. We strive to provide you with a high quality community experience. Hope you're doing OK. Use of this site is subject to our terms of use and privacy policy. I was very apprehensive about it, but my result came back fine. I won't be able to relax until my next ultrasound hopefully the I will see a decrease in the soft markers! NIPT Test Results Inconclusive! Press J to jump to the feed. Prediction of other SCA was more accurate. I had a healthy son in 2020 in which they could not determine the gender. We are part of Sonic Healthcare, an acknowledged world leader in the provision of diagnostic services, and Australias largest pathology provider. Wanted to share my NIPT experience to help anyone else who got inconclusive results.I first took my NIPT test at 10 weeks on Sept. 30. I don't think i would want to do an amnio either as I am not even high risk. Reason being: these tests utilize actual DNA and not soft markers. The company I went with uses harmony test. A failed test result will only be reported after testing of both samples) Inconclusive result. Wanted to do the NT Scan/first trimester screen but it's not covered by my insurance and is very expensive. With my first daughter there was an ECF as well that resolved itself. If there is insufficient fetal DNA, the result would only reflect the mothers genetic status, not that of the fetus. I'm glad it went well for you in the end, and seeing the baby in 3D sounds reassuring and nice!! Why should I choose Sonic to perform my NIPT? Thanks, I'm still waiting! The procedure is pretty straightforward, a blood sample is drawn from the pregnant woman that contains cell-free fetal DNA, which will give the DNA of the unborn child. Then 12 week scan showed 3mm NT. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. We keep them up because there are a ton of great conversations here and we believe you deserve to see them all. Both said due to low fetal DNA at 2.6% and 2.7% respectively. Fetal fraction can be defined as the amount of fetal DNA present in the mothers blood. You will see this come up in posts across this sub. NIPT differs from conventional prenatal screening methods in two important ways. This testing analyzes small fragments of DNA that are circulating in a pregnant woman's blood. Collection centres for all other genetic tests, Genetic counselling for other heritable disorders, Genetic counselling for selected familial disorders, Reproductive carrier screening genetic counselling. Almost 10 weeks of, this is a first for us and Ive never seen this before, we are doing further research made the first half or my pregnancy extremely tough. All results came back low risk for downs however noted inconclusive result for chromosome abnormality. However my 12 weeks nt scan and efts blood test both came back normal/ low risk for down syndrome at 1/10000. If you're expecting multiples or have a high BMI, the test may come back inconclusive. Thats when you are most likely to get an inconclusive result. I'm panicking now because I'm so worried. The reason why we cannot report a specific test usually reflects the complex biology of genetics and pregnancy rather than a technical failure in the laboratory. Clicking on the green -no result post flair- will bring up everyone who has also tagged their submission as no results/low fetal fractions and you can read up their stories/outcomes and responses (or any other topic that is common for NIPT results. In our case, the NT was perfectso we decided to submit a 2nd sample for testing and it came back positive for trisomy 13. my reason for doing the NIPT was similar to yours, haha. Surely I'm worried. juliolovesme 2 yr. ago I'm so sorry to hear that! I hope your quad screen is conclusive so you get some answers. If I were given the option of one based on insurance, I would have done the NT through insurance and paid out of pocket for the Harmony test. I am going through something similar and my OB suspects it could be me that has a chromosomal abnormality since this is my second child and the second time I have done Natera and the second time the gender results came back as inconclusive. 14/01/2022 22:06. Were they able to get a conclusive result second time round? Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. Had my harmony test at 10 weeks 3 days. Group Black's collective includes Essence, The Shade Room and Naturally Curly. What Can NIPT Tell You? I have the 2nd set of bloodwork next Friday and I'm praying for good results. I had the first level bloodwork and NT scan and they came back normal. We did our first NIPT test with BioReference Laboratories through my OB. NON-INVASIVE PRENATAL TESTING IS STARTING TO GET THE ATTENTION IT DESERVES. Do your OB rooms have an on call service you can call? I took my Nipt and it came back inconclusive ! I had two NIPT come back inconclusive. Noninvasive prenatal testing (NIPT) has become popular with many physicians in screening pregnant patients. It actually doesn't stay in your system that long. So as others have said, keep the faith if your first test is inconclusive! Are you going to get retested? Create an account or log in to participate. If the concentration of fetal DNA is below this, then the test might prove to be inconclusive. They need 4% (DNA?) Id love to know emma went. I've read online it could happen to plus size moms? Please contact the moderators of this subreddit if you have any questions or concerns. I have been a wreck and don't know what to do or why this is happening.. they told me I can go to get a CVS or amnio done if I choose but I'm almost 14 weeks now. No, NIPT is a screening test, not a diagnostic test. Create an account or log in to participate. Look up their websites and they will tell you the disorders they test for and the accuracy. sm1232, did you receive your results? Some radiologists like to comment on ALL the scans the technicians provided even the poor quality ones. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. I am overweight so that may be a contributing factor, although my OB was still very very surprised since she has had very few patients of any size receive an inconclusive result. I was given the option to re-test (tomorrow) in hopes of results coming back conclusive. When do you expect to get your results? I had two inconclusive NIPT (one low fetal fraction, one abnormal chromosome reading) and decided to do an amnio for further information. Edited to add: discussed further with the midwife, low fetal fraction was the reason for inconclusive results. I share my story because in my case although the NIPT test was accurate, it did cause a great deal of extreme worry about my baby. This is the route I took with my son (now 4.5) so I'm familiar with it. Create an account to follow your favorite communities and start taking part in conversations. We went with Myriad. Thanks for sharing your story! But higher weight makes NIPT more likely to come back with a "no call" result (although generally not until >180 kg). A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. THIS IS A SCREENING AND NOT A DIAGNOSTIC TEST. This post is meant as a welcome and quick information / resources to those who have just found this sub. To complete all the standard tests which came back fine and were able to identify that it was a boy but again, suspect maternal abmormality involving X chromosomes. Hooray I hope everyone else in limbo gets good results too! We aim to be fair and reasonable with our fee structure. Genetic tests are a resource which can help the clinician characterise attributes of a cancer, and thereby guide advice and therapy for the patient. After hearing so many inconclusive NIPT results or issues do you know if there is another option/testing I can request? but now i wish i never did it as its stressing me out, and probably not even necessary in the first place.. anyways good luck to the both of us :). It was a long 3 weeks and everything turned out fine in the end. Why Genetic testing is bad? We strive to provide you with a high quality community experience. Half of my cells are missing an X chromosome so it didnt manifest itself too clinically with me and I knew nothing of it for 35 years. and mine came back at 3.7% and couldn't be read. PlayRightParent 11.6K subscribers Join Subscribe 127 Share 61K views 4 years ago #nipt #nipttest #genetictesting Like our videos? I wouldn't necessarily do the amnio for that if the baby is otherwise healthy. I'm not sure how that works, but it doesn't necessarily indicate a problem. This time they were able. Like dont they know us preggers are already stressing?!? Noninvasive prenatal testing (NIPT) has become a popular screening test for the most common fetal aneuploidies. Just tonight I found out the second draw of blood for the Harmony. Negative impact on family and personal relationships. 3) anything that the NT scan would show (that NIPT wouldnt), the anatomy scan will also show in 20 weeks and that is a standard test for AMA people, as well. Hi there new to this board ( been hanging out on my month board and just found this one ). Update: my redraw came back low risk for everything! Although I do have a very high BMI and am aware that this can cause inconclusive NIPT results too. During pregnancy, opting for a non-invasive prenatal test has become the norm. There was another post on here about the same issue. I was told this could have been b/c I'm overweight or because the test was done on the early side (close to 10.5w). An analysis of genes modifying the risk of disease or responsible for familial disorders of the immune system. Hey there, thank you for visiting the sub. That OB needs further education about NIPT positives and how to present such information as well as knowledge of the Positive Predictive Value of NIPT based on age. The cell-free DNA tests also screen for other chromosomal abnormalities other than Down's, such as Edward's syndrome. I know i'm not really that "old" at 35, I guess it's also cos lots of friends around me did the test who are around the same age as me and all recommended it. I hope your 3rd test will give you the 4% you need! The inconclusive result was due to my fetal fraction being 4.4%. My advice: dont look at it. Im 20 years old Microarray (rare duplication? I'm waiting on my nipt test results now too. Hopefully will have before weds next week. and mine came back at 3.7% and couldn't be read. you will see them all over the place here. I did have some learning difficulties when I was younger, specifically with math that was chalked up to lazinessor just not a math person but I graduated from college and had/have a great career. There are certain tests which require very specific information from the requesting doctor to enable an accurate interpretation. Please specify a reason for deleting this reply from the community. 2005-2023Everyday Health, Inc., a Ziff Davis company. The non-invasive prenatal test (NIPT) is an accurate screening test for common trisomies, sex chromosome aneuploidies and other selected chromosome abnormalities. I'm not sure who it was but scroll back a bit and i'm sure you'll find it! Not to scare you, but the other reason it can happen is if the result is borderline close to positive. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. Yes. Just got my 2nd no result today. Results in some cases may return inconclusive or uncertain. To help you get started read our. Analysis of genes involved in drug metabolism and hypersensitivity, allowing clinicians to prescribe with confidence. Reasons behind an inconclusive prenatal paternity test. Went back yesterday and did a redraw, and now I'm hoping this one takes. Archived discussions are usually a bit older and not as active as other community content. Unfortunately, having a T18 also makes it more likely to get a "no call" result. Hope you're doing OK. Hi all. haha our timing for the tests sound quite similar, i am waiting for the referral to see the genetic counselor, so for now will have to wait and see what they recommend. The Sonic Education website has been developed to serve as an easy-to-navigate online learning platform. Definitely something to bring up. Since the nIPT is inconclusive youll have this redrawn but in the mean time I would get the triple screen. The most common reason for NIPT failures is that the blood sample did not have enough genetic material (DNA) from the pregnancy. I had both. The first draw I did at 12 weeks and second draw did at around 13 weeks 6 days. Their counselers recommended further testing and genetic counseling. Hope you get your peace of mind as well! Possible reasons for this include: Timing of blood draw - there is a higher chance for the test to fail when the blood draw is done too early in the pregnancy, Everything came back low risk, so relieved and thankful. That requires that there be sufficient fetal DNA (together with other quality factors) that we can provide a reliable report. POSITIVE PREDICTIVE VALUE CALCULATOR FOR NIPT RESULTS https://www.perinatalquality.org/Vendors/NSGC/NIPT/, *I highly suggest you first read through everything in main post located here to start: https://www.reddit.com/r/NIPT/comments/ecjj5v/welcome_to_rnipt_the_sub_for_abnormal_nipt/, *After this head over to this post about the actual individual results: https://www.reddit.com/r/NIPT/comments/itmyjw/my_nipt_results_show_this_abnormality_what_does/. Have you had the NT scan done? Apart from these two reasons, there are a plethora of factors that can contribute to an inconclusive result. Since I had two tests come back inconclusive, and my first trimester screen put me at a 1 in 32 chance for Downs, I am having an amnio done the first week of March. Have you gotten your NIPT results back yet? My NIPT came up inconclusive the first time as well. What if NIPT cannot make an assessment? NIPT is most often used to screen for trisomy. Why did repeat testing not give a result? I had the test done and didn't have any issues with the results. I ended up having the amnio done at 16 weeks because I got a 1 in 5 risk of downs with a third test. It has to be at least above 4 percent to give a conclusive result. (Don't quote me on that, just what I've read.). If there is insufficient fetal DNA. Hope you get some answers soon. Please specify a reason for deleting this reply from the community. Your post will be hidden and deleted by moderators. Sounds right on the money, I got turned away for my first babys boot as it was a Friday an they send the test on the Monday and they said they would have it sitting there all weekend its not recommended. If the concentration of fetal DNA is below this, then the test might prove to be inconclusive. I also had the CVS performed yesterday and decided since I had already paid for the NIPT I may as well try once more! I had two inconclusive nipt tests at 12 and 13 weeks. I'll do my 3rd test at nearly 16 weeks. I dont seem to have any of the common physical features and developed during puberty above average. Inconclusive Panorama DNA test results! So frustrating!!! Get weekly updates on baby and your body. It lead to 3 weeks of PURE hell. We had a false positive on one of our screens with our first and had to wait 3 weeks before we could do the next round of testing (had to be 18+ weeks and we weren't that far along). I hope this helps you consider an alternative, less stressful reason. ), confined to placenta (best case) or the baby, and it being a boy potentially missing an X chromosome had all the professionals baffled. The DNA sample of the potential father is collected through a buccal swab, and the two samples are compared to determine paternity. 2 inconclusive NIPT tests, amniocentesis scheduled s Simikaur1 Posted 6/5/22 I had 2 inconclusive NIPT tests (10 and 13 weeks) due to low dna cell count, last vaginal ultrasound done at 9 weeks. This means that the result is not clear and a result cannot be produced. Please whitelist our site to get all the best deals and offers from our partners. Its 100% accurate (I believe). Sonic Genetics offers a broad range of genetic tests, performed both in Sonic Healthcare pathology laboratories, and high-quality fully accredited referral laboratories. We are repeating the assay on the same sample you have already sent and we should have that result on Wednesday. Note that once you confirm, this action cannot be undone. Thank you, I am hoping it's just a silly lab error. Diagnostic fetal chromosome analysis should be offered after abnormal NIPT or in the presence of cystic hygromas despite normal NIPT. The #1 app for tracking pregnancy and baby growth. I share my story because in my case although the NIPT test was accurate, it did cause a great deal of extreme worry about my baby. Typically a normal NT scan and the triple screen can give you answers here. Just thought I'd update you or anyone else who may read this board. The information on this website is provided for your general information and is not a substitute for the specific advice of your treating doctor. Its nothing to worry about, it was probably just a bit too early! No? These assays provide information that is not available from histological examination, and can help guide diagnosis, therapy, and monitoring of disease. This was simply a technical issue within the laboratory. Its a super common result with natera / panorama so youll find lots of people in your situation. Just thought I'd update you or anyone else who may read this board. why is my nipt test inconclusive. It has to be at least above 4 percent to give a conclusive result. Meet other parents of December 2019 babies and share the joys and challenges as your children grow. So doesnt seem like Im low risk but My obgyn wants to refer me to see a geneticist to discuss possible next steps. Yes. During this difficult time you may be looking information about what the NIPT results you received mean. Fingers crossed your 12 week scan comes back ok. Welcome to Abnormal NIPT screening results! If the concentration of fetal DNA is below this, then the test might prove to be inconclusive. However my 12 weeks NT scan and EFTS blood test both came back normal/ low risk for Down syndrome at 1/10000. sm1232, did you get the results to your CVS? Just got this email from the lab doing my test!!! So, a "normal" NIPT result doesn't guarantee a healthy baby, and an "abnormal" result doesn't mean your baby definitely has a certain condition. (High HCG, low PAAP-A, normal nuchal translucency.) I think in my case, my first test must have been borderline. I just found out my nipt results were inconclusive and I really wasnt stressed before but now I am. Confirmed by amnio a week later. Best of luck! My OB says she sees it all the time and they usually resolve themselves. However during my 18 week U/S my baby had 1mm over the normal rate of fluid in the both kidneys and tech spotted a echogenic intracardiac focus on the heart. Results in some cases may return inconclusive or uncertain. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. Also horrible stats about high incidence of redraw samples being inconclusive too. All rights reserved. Sex chromosome aneuploidy was frequently suspected on NIPT. Don't despair if your grandmother's wisdom turns out to be little more than a good guess. Noninvasive prenatal tests, or NIPTs, screen for an array of rare genetic conditions. I just found out today at 12.5 weeks that my test was not conclusive. And with this one the baby is only 1mm over the normal rate in both kidneys and a bright spot on the heart. Has anyone else had this happen to them? You always have a right to speak to a genetic counselor after an abnormal NIPT result and this should be provided for you by your OB. Start by selecting which of these best describes you! As always, take any information given here and online for what it is - information - and always discuss further treatment plans with your physicians, however with caution. Please guide us. Contact us today to learn more about everything that we can do for you. GAH! I'm sure that it's not a definitive, but I like getting the facts and this has helped me be a little more mentally prepared. I know its scary and I know my specific situation seems to be rare as far as lack of symptoms and what not so I cant give you any medical advice, but I can tell you that I am living a wonderful and fullfilling and I wish the same for your daughter no matter what the outcome. Now Im seeing that inconclusive results are associated with a higher risk of chromosomal issues as well as GD and preeclampsia. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. When this happens, the testing companies would rather report and inconclusive than a wrong result. Thank you for sharing your personal story with me. It happened to me with my blood results from the triple screening. In medicine, a laboratory test that checks for certain genes, proteins, or other molecules in a sample of tissue, blood, or other body fluid. Inconclusive NIPT results. What to Expect has thousands of open discussions happening each day. I'm sure that it's not a definitive, but I like getting the facts and this has helped me be a little more mentally prepared. Warning: fopen(/nfs/c05/h05/mnt/158483/domains/lomejordelboxeo.com/html/wp-content/uploads/wp-file-manager-pro/fm_backup/.htaccess): failed to open stream: Permission . I am booked for a 12 week scan this week. Anyone else have this come up? This updates the flair on your username IN THIS SUB ONLY. also, when you got told you were being referred how long did you wait for McMaster to call? Negative impact on family and personal relationships. I have been feeling so worry and pessimistic ever since the NIPT result. All rights reserved. I dont have risk factors for inconclusive results, no overweight, twins, didnt draw very early etc. So i was referred to do nipt test. Not all physicians are actually up to date with NIPT testing, what results mean or how to present such SCREENING results to a patient. did east germany have money? Anyone else experienced this? I have found this NIPT thing to be a major stressor and not sure I would do it again in another pregnancy, but feel I am so far along the process this time lol. I would request PaPPa and hcg and NT screen which is the triple screen. NIPT is commonly used for chromosomal disorders that are caused by the presence of an extra (triploidy) or missing copy (aneuploidy) of a chromosome. Genetic tests are frequently not covered by Medicare or private health insurance, Every sample from a patient is tested to determine whether there is sufficient feto-placental DNA to provide a reliable result. What the heck, now so stressed! This has been really hard on me not knowing but there are so many what ifs.. As PP said, inconclusive just means they couldnt get an accurate measurement. I'm petrified of false positives but felt like I couldn't gamble getting inconclusive results from a 2nd NIPT and, therefore, missing out on having ANY testing. My NIPT came up inconclusive the first time as well. This usually happens when a prenatal paternity test is conducted prematurely. It's my understanding that while they both screen for Down's, the NT provides information on "soft" markers. *** Your email address will not be published. When the test is repeated, about 1 in 3 repeat NIPT samples comes back with no result. However, they got all the ones they needed for the NIPT which were good. The Sonic Genetics website includes general information regarding genetic testing, as well as specific information about particular tests. I am a bot, and this action was performed automatically. My ex husband and I struggled to conceive for years. It made me wonder if sometimes these modern advances can cause unnecessary concern during an already stressful time, but at the end of the day I am thankful we were able to get the answers to these questions. Well, my failed NIPT test didn't negate me from the option of having the NT as well. harry hill family. Below this, the nipt returns the result "inconclusive." after the nipt results: Inconclusive sca an inconclusive sca. This discussion is archived and locked for posting. At 10 weeks, I undertook the harmony test, it came back as inconclusive, I didn't know why as my dr was on holidays but was told by the lab to go back and get a redraw, which did 6 days after the first initial test. Here are 3 factors that can lead to such a result. Mine should** be in tomorrow or Friday. This usually happens when a, Non-Invasive Prenatal Baby Gender Blood Test. for the test to get accurate results. The #1 app for tracking pregnancy and baby growth. This educational content is not medical or diagnostic advice. Hi bubblegum, I am in the same situation and am having a retest next week. First, conventional screening methods which . They said since they dont know which of my cells are missing the X because they only take a sample size, its hard to pinpoint what is impacted or not. As of now I have no cardiac or kidney problems but I will see specialists when this baby is born just to be sure. Group Black's collective includes Essence, The Shade Room and Naturally Curly. Level 17, Grosvenor Place, 225 George Street, Sydney, NSW 2000. That only happens in 1% of tests. Pregnancy. Reason being: the labs offering these tests seem to only bill people paying out of pocket $250. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. What Does NIPT Not Test For? Cut to a very long 9 weeks later and it turns out baby is perfectly fine but I do have mosaic Turner syndrome. Run by research scientists who are experts in human DNA diagnostics, we also offer express shipping services to reduce waiting time. Unlike most DNA, which is found inside a cell's . In some cases, a test result might not give any useful information. Can you call the genetic counsellor at the company that does the NIPT and ask for information on specifically what they found (or didn't find) that made it inconclusive what the results might mean? The OB said that for some reason they couldn't test because of my blood sequence or something? Source: www.babycenter.com.au. There are some options filled in, but you can also write in your own result. While it is not certain by any means, getting no result during a NIPT test might point toward an increased chance of chromosomal abnormalities. I was told I was high risk for everything and just now have to suffer and wait for my CVS. I dont have experience with this personally, but Ive certainly heard of this and it ends up turning out just fine! Use of this site is subject to our terms of use and privacy policy. It's so crazy! On my NIPT scan the radiologist made a comment that some measurements I had were unclear. Acosta decided to take advantage of non-invasive pregnancy testing, or NIPT, a relatively new prenatal screening method. In approximately 1% of women, the NIPT result is unable to provide an assessment about one or more of the disorders being screened, or cannot provide an assessment of fetal sex. Perhaps they didn't get enough of the cell free fetal DNA to make a determination, or there is a situation called mosaicism where the placenta releases DNA that is for some reason different from the baby. Which made me really nervous, would that really be necessary, when my other results (the NT and efts) were fine with low risks? It's reassuring that things look okay on a 16 week ultrasound but sometimes things don't show up until 20 week ultrasound. Symptmes de grossesse ne jamais ignorer, Moyens naturels pour dclencher l'accouchement. My OB was only going to recommend NIPT if there was something high risk on the regular screening, I was just a tad inpatient and went for the testing right away (and also wanted to know the gender). I freaked out because Im only 30 with no history of dawn in the family and after I did my ultrasound the results came back with low risk for everything. I was 11 weeks and 2 days when my blood was drawn. Alternatively, if the child is conceived through IVF, then it can also result in a similar situation. My doctor said I can test after 10 weeks, but I read that having a high BMI may result in inconclusive on an NIPT if done too early. Just waiting for the office to call back to rebook. how to find the length of an oval track; how long to cook baked potato on grill; george pearsons house; distance from thunder bay to manitoba border Anyone else have this come up? It's. . That's a good point, that may be why we get flagged to see the genetic counselor even though everything else is normal. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. Hello! I wouldn't bet on the NT measurements to guide you. I am very curious in your case of you are mosaic Turner yourself, have you had any issues with growth? Is the NIPT test conclusive? I was worried too, so I did a bit of research on it. No problems and the procedure was not nearly as bad as I thought. Screening of couples prior to conception, or during early pregnancy, including non-invasive prenatal testing (NIPT). Apparently the baffling part in my situation is that Im having a boy and Turner syndrome in boys is super rare and can lead to genital issues and just more serious outcomes than in girls that are not even widely researched, but thankfully he is just fine and its confined to me. Show your support by. Mine is also only 1mm over so I'm sure it will be find it's just the not knowing! I will keep you all informed about this issue. This is so when you speak to others, they immediately understand your situation AND you can see their situation summary. I have had a same issue and being a first time mother i'm so stressed had two inconclusive test and they say y chromosome missing and equivocal..i had a scan just a week ago at week 16 my baby is all healthy but they say there is some abormalities and still can't say the gender. It can come with its own set of risks. Are you booked for your 12 week scan? Please also place a flair on your username which can be done by going to the right side of the sub -- community options -- and update username flair. info@sonicgenetics.com.au 1800 010 447 (Australia only) 1800 515 119 Of course, this can be dispelled with subsequent retests. There are 2 main sticky posts about what NIPT is, how it works, what it can miss and how false positives happen, sono findings, and your chances of a true positive after NIPT. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. We just got our results back and have a perfectly healthy . Costs about 50 bucks. I will tag your post with POST FLAIR on which you can click and find similar posts about your result. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Sorry youve gone through this stress xx. Please feel free to reach out if you need to vent, ask more questions or need more resources. They told me there wasn't enough fetal DNA in my blood to accurately complete the test. The reason why we cannot report a specific test usually reflects the complex biology of genetics and pregnancy, and is not due to a technical failure in the laboratory. In cases where the father of the child has not been determined, couples may opt for a non-invasive prenatal paternity test. Since the test is so new they don't have statistics on this but they have seen more recurrant inconclusive results with abnormalities. Same happened to us. I just found out today at 12.5 weeks that my test was not conclusive. Which according the clinical labs, they can taste at this rate. Low Fetal Fraction. 1 DNA is usually located within cells. Its been very interesting learning this for sure and although my symptoms are extremely mild and nothing showed up for my daughters testing last year when I was pregnant with her I still of course hope this wasnt passed down. It's most likely the mosaicism, or a twin embryo that did not take. Hoping all is ok. Edited to add: discussed further with the midwife, low fetal fraction was the reason for inconclusive results Fingers crossed for u! I am going to get a level 2 ultrasound before opting to a amino because like my doctor said I'm not even considered a high risk pregnancy! She actually specifically said that it didn't mean anything, bad or good. Manal92! Community for those with abnormal or discordant Noninvasive Prenatal Testing (NIPT/NIPS) screening results: FALSE POSITIVE, FALSE NEGATIVE, TRUE POSITIVE & those stuck in limbo. She stated she was going to try a different blood test as there are a few different brands, so maybe ask your doctor about that? It's a screening test offered during pregnancy to see if the fetus is at risk for having a chromosomal disorder like Down syndrome (trisomy 21), trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome). I really do feel for those that don't have as many affordable options. your gp will sort it out for you love. Easy to overthink (I sure did) and assume the worst - feels like Sod's law at the . Here is a list of the most common questions we are asked. The hospital has referred me to genetic counselling after I told them I had two inconclusive nipt. Our fees are set at a level to ensure that we can deliver a high quality and comprehensive genetic pathology service to you. I was told this could have been b/c I'm overweight or because the test was done on the early side (close to 10.5w). Someone please help calm my nerves! It provides information on the placenta and the baby's growth. And what was your BMI? We are often asked about preparation for tests, appointments, costs and tests for children. Please whitelist our site to get all the best deals and offers from our partners. Not even gender. 5/30: 4th beta: 17,852 + saw fetal pole and heard heartbeat! Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. Our commitment to quality means that we will only provide a result when there is very clear evidence for, or against, the presence of a specific disorder. Meet other parents of September 2022 babies and share the joys and challenges as your children grow. I hope this helps. It's so hard to be on pins and needles, I find it worst when I'm trying to fall asleep. Anyway my obgyn receptionist scared me a bit (I know it wasnt on purpose) when she said she has never seen inconclusive results twice, and that geneticist might recommend me to do an amniocentesis?? Certain prenatal screening tests like NIPT are very accurate for conditions such as Down syndrome, but less so for rare genetic conditions. NIPT analyzes fragments of the baby's DNA found circulating in a pregnant person's blood. Links to useful external resources of genetic information for clinicians. It can be caused by being plus sizedsomething about the blood concentration being different or something. NIPT also includes a study of the sex chromosomes, but a result is not always possible. Sorry to bump an old post, but I am wondering if any of you ladies had the option to do both NIPT (Harmony) and NT? Ugh. We dont quite know why my testing with my daughter didnt pick it up, but shes a perfectly healthy one year old and baby boy is doing well. Just tonight I found out the second draw of blood for the Harmony test came back inconclusive. Childhood-onset disorders due to new cytogenetic abnormalities and inherited mutations. Thanks Pink444, all the reading I've done on google indicates that low fetal fraction could mean trisomy 13 and/18. I guess this is not so uncommon. She mentioned they might suggest using another company to do the bloodtest (my NIPT were done by lifelab). It could either actually be me (and could it be passed down? When cells break down, they release . We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. 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The gender others have said, keep the faith if your first test is repeated, about in. Compared to determine paternity n't bet on the placenta and the baby 's growth pessimistic... 2.7 % respectively results now too like Sod & # x27 ; doing. Nothing to worry about, it was but scroll back a bit too early at nearly 16 weeks of! Problems but i do n't have statistics on this but they have seen more recurrant inconclusive.... Fraction could mean trisomy 13 and/18 on that, just what i 've read online it could actually.